Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progression

已完结 20 由刘志新发布于 2026/4/2 17:14:29

DOI:10.1101/2024.04.03.588024
作者：Sarah SK Yue, Yin Tong, Hoi Cheong Siu, Siu Lun Ho, Simon YK Law, Wai Yin Tsui, Dessy Chan, Yuanhua Huang, Annie SY Chan, Shui Wa Yun, Ho Sang Hui, April S Chan, Siu Tsan Yuen, Hans Clevers, Suet Yi L
文献类型：期刊论文
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Abstract：Objective: Gastric intestinal metaplasia (IM) is a pre-cancerous stage spanning a morphological spectrum that is poorly represented by human cell line models. We aim to establish and charact

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