Adeno-associated virus (AAV) 9-mediated gene delivery of Nurr1 and Foxa2 ameliorates symptoms and pathologies of Alzheimer disease model mice by suppressing neuro-inflammation and glial pathology

已完结 10 由 wdf 发布于 2026/4/2 13:28:37

DOI:10.1038/s41380-022-01693-6
作者：Yunseon Yang,?Min-Jong Seok,?Ye Eun Kim,?Yunjung Choi,?Jae-Jin Song,?Yanuar Alan Sulistio,?Seong-hoon Kim,?Mi-Yoon Chang,?Soo-Jin Oh,?Min-Ho Nam,?Yun Kyung Kim,?Tae-Gyun Kim,?Heh-In Im,?Seong-Ho Koh,?
文献类型：期刊论文
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Springer

Abstract：There is a compelling need to develop disease-modifying therapies for Alzheimer’s disease (AD), the most common neuro-degenerative disorder. Together with recent progress in vector developme

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