Macrocyclization of Maleimide-Decorated Peptides via Late-Stage Rh(III)-Catalyzed Trp(C7) Alkenylation

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DOI:10.1021/acs.orglett.3c00601
作者：Yu Zhang,?Shulei Hu,?Yazhou Li,?Yongkun Wang,?Tao Yu,?Qiangqiang Chen,?Jiang Wang* and Hong Liu*,?
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：Here, we report a novel strategy for constructing maleimide-containing peptides and cyclic peptides using Rh(III)-catalyzed tryptophan (Trp) (C7) alkenylation, which is challenging due to th

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