A renaissance in targeting the PI3K/AKT/mTOR pathway.

待确认 10 由合同法头发发布于 2026/4/6 17:18:57

DOI:10.1038/s41573-026-01388-5
作者：Sarah E Conduit,Neil Vasan,Jennifer R Brown,Matthew W D Perry,Bart Vanhaesebroeck
文献类型：期刊论文
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Nature

Abstract：The PI3K/AKT/mTOR pathway represents an excellent drug target, given its proven druggability and roles in cancer, immune regulation and genetic disorders. However, although some agents targe

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