Prime editor with rational design and AI-driven optimization for reverse editing window and enhanced fidelity

已完结 10 由 zhizhi 发布于 2026/4/8 15:08:25

DOI:10.1038/s41467-025-60495-w
作者：Chao Yang, Qingxiao Fang, Mengyu Li, Jin Zhang, Rui Li, Tianxing Zhou, Keshan Wang, Jie Deng, Xiuchao Wang, Chongbiao Huang, Yukuan Feng, Xiaoping Zhang, Lei Shi, Changhao Bi, Xueli Zhang, Jun Yu, Jih
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：Prime editing (PE) is a precise tool for introducing genetic mutations in eukaryotes. Extending the efficient editing scope and mitigating undesired byproducts are possible. We introduce rev

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