Immune evasive DNA donors and recombinases license kilobase-scale writing.

已完结 10 由 121 发布于 2026/3/16 10:59:39

DOI:10.1038/s41586-026-10241-z
作者：Connor J Tou,Keqiang Xie,Joana Ferreira da Silva,Pazhanichamy Kalailingam,Eliz Amar-Lewis,David Rufino-Ramos,William Sawyer,Madeline L Eller,Jakob Starzyk,Ishita Majumdar,Jiao Wang,Danna Lee,Shaobo Ya
文献类型：期刊论文
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Nature

Abstract：Genome-editing technologies that use recombinases to insert kilobase-scale DNA sequences into mammalian genomes canonically require large double-stranded DNA (dsDNA) donors1,2. However, dsDN

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