Rational design of 1H-pyrrole-2-carboxylic acid inhibitors of NDM-1 metallo-β-lactamase restoring β-lactam efficacy against resistant Enterobacterales

已完结 10 由 phoebe9203 发布于 2026/3/17 9:41:07

DOI:10.1016/j.ejmech.2025.118376
作者：Tatiana S. Shkuratova , Kirill V. Rychev , Vitaly G. Grigorenko , Irina P. Andreeva , Natalia E. Grammatikova , Alexander S. Tikhomirov , Alexey M. Egorov , Andrey E
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：Antimicrobial resistance mediated by metallo-β-lactamases (MBLs) represents a critical challenge for the efficacy of β-lactam antibiotics. Here, we report the design, synthesis, and evaluati

应助信息

求助已完结，文件已删除 如有需求请重新发布求助一键发布

感谢使用Book学术
本站所有文献仅供个人学习和参考，请勿将文件进行传播。共同遵守网站规定和相关知识产权规定。

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:其它数据库Unravelling key factors controlling homogeneous crystallization during phosphorus recovery: From the perspective of crystallization kinetics