SUMOylation of the cardiac sodium channel NaV1.5 modifies inward current and cardiac excitability

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DOI:10.1016/j.hrthm.2023.07.067
作者：Jin-Young Yoon PhD ,?Alexander M. Greiner MD, PhD ,?Julia S. Jacobs MS ,?Young-Rae Kim PhD ,?Tyler P. Rasmussen MD, PhD ,?William J. Kutschke MS ,?Daniel S. Matasic MD, PhD ,?Ajit Vikram PhD ,?Ravinde
文献类型：期刊论文
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Elsevier

Abstract：BackgroundDecreased peak sodium current (INa) and increased late sodium current (INa,L), through the cardiac sodium channel NaV1.5 encoded by SCN5A, cause arrhythmias. Many NaV1.5 posttransl

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