SUMOylation of the Cardiac Sodium Channel NaV1.5 Modifies Inward Current and Cardiac Excitability

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DOI:10.1101/2022.12.26.521675
作者：Jin-Young Yoon,?A. Greiner,?J. Jacobs,?Young‐Rae Kim,?W. Kutschke,?Daniel S. Matasic,?A. Vikram,?R. R. Gaddam,?H. Mehdi,?K. Irani,?B. London
文献类型：期刊论文
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Abstract：Background Decreased peak sodium current (INa) and increased late sodium current (INa,L), through the cardiac sodium channel NaV1.5 encoded by SCN5A, cause arrhythmias. Many NaV1.5 post-tran

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