H3K18 lactylation promotes osteogenic differentiation of periodontal ligament stem cells via IGF2BP1/m⁶A/BMP2.

已完结 10 由祁茵发布于 2026/3/20 14:24:46

DOI:10.1016/j.bcp.2026.117899
作者：Zhuo Wang, Beimiao Weng, Jing Qian, Huayan Guo
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：The osteogenic commitment of periodontal ligament-derived stem cells (PDLSCs) represents a critical therapeutic target for managing periodontitis and restoring tissue homeostasis. While lact

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H3K18 lactylation promotes osteogenic differentiation of periodontal ligament stem cells via IGF2BP1/m6A/BMP2.

H3K18 lactylation promotes osteogenic differentiation of periodontal ligament stem cells via IGF2BP1/m⁶A/BMP2.