Discovery of human gut phage-encoded anti-CRISPR proteins unveils diverse mechanisms for phages to evade type II CRISPR immunity

待确认 20 由 zt 发布于 2026/3/19 20:32:25

DOI:10.1016/j.chom.2026.02.017
作者：Shengjian Yuan, Heng Zhu, Menghao Yu, Huizhen Jia, Shiwen Peng, Yingfei Ma
文献类型：期刊论文
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Abstract：Phages encode diverse anti-CRISPR (Acr) proteins to counteract bacterial CRISPR-Cas systems. However, gut phage Acrs remain poorly characterized. Using an integrated bioinformatics and high-

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