Loss of MFE-2 impairs microglial lipid homeostasis and drives neuroinflammation in Alzheimer’s pathogenesis

已完结 10 由 (#^.^#) 发布于 2026/6/16 21:47:31

DOI:10.1038/s43587-025-00976-1
作者：Min Gao, Jing Bai, Fangzhou Lou, Yang Sun, Zhikai Wang, Xiaojie Cai, Yan Li, Fengjiao Zhang, Jihuan Liang, Xiangxiao Li, Yue Wu, Ziyang Zhang,&nb
文献类型：期刊论文
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Nature

Abstract：Dysregulated lipid metabolism promotes persistent microglial activation and neuroinflammation in Alzheimer’s disease (AD), but the underlying pathogenic mechanisms remain to be elucidated, a

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