A druggable redox switch on SHP1 controls macrophage inflammation

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DOI:10.1038/s41589-026-02163-8
作者：Mei Ying Ng, Meredith N. Nix, Guangyan Du, Ivan Davidek, Nils Burger, Sanghee Shin, Sean Toenjes, Haruna Takeda, Megan Cheah Xin Yan, Bingsen Zhang, Haopeng Xiao, Shelley M. Wei, Hyuk-Soo Seo, Sirano
文献类型：期刊论文
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Nature

Abstract：Immunological proteins are major disease targets, yet most remain undrugged. Post-translational redox modification of cysteine residues has emerged as an important mode of immune cell regula

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