A CHKA-PML autophagy checkpoint enables tumors to evade glutamine starvation.

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DOI:10.1073/pnas.2523253123
作者：Ruijie Wang,Leixi Cao,Xianwei He,Rick Francis Thorne,Qichen Wu,Caoyuan Ding,Jinjing Zhang,Mengfan Li,Zeyuan Shi,Xinyi Dong,Jing Li,Hongxiang Li,Suhua Gao,Jinming Li,Xu Dong Zhang,Lei Jin,Tianli Fan,Mi
文献类型：期刊论文
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Proceedings of the National Academy of Sciences of the United States of America (PNAS)

Abstract：Glutamine metabolism is essential for tumor cell proliferation and biosynthesis. However, solid tumors often face chronic glutamine deprivation, and the underlying adaptive mechanisms remain

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