Process Development of the Novel LpxC Inhibitor T-1228. Part 2: Synthesis of the Malonamide Core and the Final Intermediate

已完结 10 由小太阳发布于 2025/12/31 13:48:09

DOI:10.1021/acs.oprd.5c00166
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.oprd.5c00166

American Chemical Society (ACS)

Abstract：The novel LpxC inhibitor T-1228 is a candidate drug molecule for multidrug-resistant Gram-negative bacterial infection. This report describes the synthesis of the malonamide derivative,(2S)-

应助信息

求助已完结，文件已删除 如有需求请重新发布求助一键发布

感谢使用Book学术
本站所有文献仅供个人学习和参考，请勿将文件进行传播。共同遵守网站规定和相关知识产权规定。

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:American Chemical Society (ACS)Process Development of the Novel LpxC Inhibitor T-1228. Part 3: Optimization of the Deprotection Reaction and the Crystallization for the Final Step of API Synthesis