Claudin 18.2-targeting antibody–drug conjugate CMG901 in patients with advanced gastric or gastro-oesophageal junction cancer (KYM901): a multicentre, open-label, single-arm, phase 1 trial

已完结 10 由 Luke 发布于 2026/1/5 11:02:40

DOI:10.1016/s1470-2045(24)00636-3
作者：Dan-Yun Ruan, Fu-Rong Liu, Xiao-Li Wei, Su-Xia Luo, Zhi-Xiang Zhuang, Zhen-Ning Wang, Fu-Nan Liu, Yan-Qiao Zhang, Jian-Wei Yang, Zhen-Dong Chen, Yong-Sheng Wang, Jun-Ye Wang, Xiao-Hua Liang, Xiao-Jie
文献类型：期刊论文
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Elsevier

Abstract：BackgroundCMG901 is a novel first-in-class antibody–drug conjugate with a humanised anticlaudin 18.2 antibody linked to microtubule-disrupting agent monomethyl auristatin E. We aimed to asse

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