Development of a Rapid Scale-Up Synthesis of (S)-N-(8-((2-Amino-2,4-dimethylpentyl)oxy)-5H-chromeno[3,4-c]pyridin-2-yl)acetamide, a Potent Adaptor-Associated Kinase 1 Inhibitor

已完结 10 由 hahah 发布于 2025/12/13 14:59:03

DOI:10.1021/acs.oprd.1c00452
作者：Jianqing Li*,?Daniel Smith,?Joseph Pawluczyk,?Subramaniam Krishnananthan,?Bei Wang,?Xiaoping Hou,?Rulin Zhao,?James Kempson,?Dawn Sun,?Shiuhang Yip,?Dauh-Rurng Wu,?Nageswararao Maddala,?Muthalagu Vetr
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：(S)-N-(8-((2-Amino-2,4-dimethylpentyl)oxy)-5H-chromeno[3,4-c]pyridin-2-yl)acetamide (1) is a potent adaptor-associated kinase 1 inhibitor, which may have the potential to treat neuropathic p

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