Lessons learned in linking PROTACs from discovery to the clinic.

已完结 10 由达姆发布于 2025/12/15 16:13:41

DOI:10.1038/s41570-025-00784-6
作者：Andy Pike,?Esther C Y Lee,?Iacovos N Michaelides,?Markus Schade,?Ankit Sharma,?James S Scott,?Abhishek Srivastava
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：Targeted protein degradation has the potential to deliver greater efficacy than conventional receptor antagonists or enzyme inhibitors and address previously undruggable targets. This has dr

应助信息

求助已完结，文件已删除 如有需求请重新发布求助一键发布

感谢使用Book学术
本站所有文献仅供个人学习和参考，请勿将文件进行传播。共同遵守网站规定和相关知识产权规定。

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:其它数据库Graph Learning on Instruction Stream-Augmented CFG for Malware Variant Detection