Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanoma

已完结 10 由 sunshine洁发布于 2025/12/15 15:44:20

DOI:10.1016/j.immuni.2025.10.004
作者：Annabell Bachem, Michele Clarke, Geraldine Kong, Ilaryia Tarasova, Lachlan Dryburgh, Lindsay Kosack, Ariane R. Lee, Lewis D. Newland, Teagan Wagner, Emma Bawden, Kah Min Yap, Michael D. Wilson, Sven E
文献类型：期刊论文
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Elsevier

Abstract：A range of microbiota species correlate with improved cancer outcomes in patients and confer protection in pre-clinical mouse models. Here, we examined how microbiota regulate CD8+ T cell im

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