Single-cell RNA profiling of blood CD4+ T cells identifies distinct helper and dysfunctional regulatory clusters in children with SLE

已完结 10 由 sunshine洁发布于 2025/12/15 14:54:52

DOI:10.1038/s41590-025-02297-2
作者：Preetha Balasubramanian,?Uthra Balaji,?Marina Silva Santos,?Jeanine Baisch,?Cynthia Smitherman,?Lynnette Walters,?Paola Sparagana,?Lorien Nassi,?Katie Stewart,?Julie Fuller,?Terry Means,?Virginia Savo
文献类型：期刊论文
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Nature

Abstract：To characterize the complexity of the CD4⁺ T cell compartment in patients with systemic lupus erythematosus (SLE), we performed single-cell RNA sequencing of sorted blood CD4⁺ T cells from p

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