Structure-activity relationship study of RSL3-based GPX4 degraders and its potential noncovalent optimization

已取消 20 由胖子发布于 2025/12/17 19:40:02

DOI:10.1016/j.ejmech.2023.115393
作者：Cangxin Zheng ,?Chao Wang ,?Dan Sun ,?Han Wang ,?Bingru Li ,?Guoquan Liu ,?Zhenming Liu ,?Liangren Zhang ,?Ping Xu
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：Ferroptosis is an iron-dependent, non-apoptotic form of cell death involving in various disease processes. Mechanistically, glutathione peroxidase 4 (GPX4) which belongs to the redox enzyme

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