4-Acyl Pyrrole Capped HDAC Inhibitors: A New Scaffold for Hybrid Inhibitors of BET Proteins and Histone Deacetylases as Antileukemia Drug Leads

已完结 10 由小小发布于 2025/12/18 9:31:10

DOI:10.1021/acs.jmedchem.1c01119
作者：Linda Sch?ker-Hübner,?Robin Warstat,?Heinz Ahlert,?Pankaj Mishra,?Fabian B. Kraft,?Julian Schliehe-Diecks,?Andrea Sch?ler,?Arndt Borkhardt,?Bernhard Breit,?Sanil Bhatia,?Martin Hügle,?Stefan Günthe
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：Multitarget drugs are an emerging alternative to combination therapies. In three iterative cycles of design, synthesis, and biological evaluation, we developed a novel type of potent hybrid

应助信息

求助已完结，文件已删除 如有需求请重新发布求助一键发布

感谢使用Book学术
本站所有文献仅供个人学习和参考，请勿将文件进行传播。共同遵守网站规定和相关知识产权规定。

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:其它数据库CLONING AND EXPRESSION OF A LIPASE GENE FROM PSEUDOMONAS AERUGINOSA INTO E.coli