Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer’s disease

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DOI:10.1007/s00401-023-02559-z
作者：Yuan Cheng,?Chen-Yang He,?Ding-Yuan Tian,?Si-Han Chen,?Jun-Rong Ren,?Hao-Lun Sun,?Man-Yu Xu,?Cheng-Rong Tan,?Dong-Yu Fan,?Jie-Ming Jian,?Pu-Yang Sun,?Gui-Hua Zeng,?Ying-Ying Shen,?An-Yu Shi,?Wang-Shen
文献类型：期刊论文
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Springer

Abstract：Cerebral amyloid-β (Aβ) accumulation due to impaired Aβ clearance is a pivotal event in the pathogenesis of Alzheimer’s disease (AD). Considerable brain-derived Aβ is cleared via transportin

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