Lactate Promotes Collagen Expression, Proliferation, and Migration through H3K18 Lactylation–Dependent Stimulation of LTBP3/TGF-β1 Axis in Keloid Fibroblasts

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DOI:10.1016/j.jid.2025.04.044
作者：Jing-Jing Gu ,&nbsp;Cheng-Cheng Deng ,&nbsp;Qing An ,&nbsp;Ding-Heng Zhu ,&nbsp;Xue-Yan Xu ,&nbsp;Zheng-Zheng Fu ,&nbsp;Zheng-Yang Zhou ,&nbsp;Zhili Rong ,&nbsp;Bin Yan
文献类型：期刊论文
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Elsevier

Abstract：Keloids are fibroproliferative dermal lesions characterized by unrestrained fibroblast proliferation, collagen overproduction, and persistent enlargement. Lactate has been suggested to regul

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