Ortho-Deuteration of Aromatic Aldehydes via a Transient Directing Group-Enabled Pd-Catalyzed Hydrogen Isotope Exchange

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DOI:10.1021/acs.joc.1c01411
作者：Junhua Kong,?Zhi-Jiang Jiang,?Jiayuan Xu,?Yan Li,?Hong Cao,?Yanan Ding,?Bencan Tang,?Jia Chen,?Zhanghua Gao*
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：A practical and scalable ortho-selective deuteration of aromatic aldehydes was accomplished by Pd-catalyzed hydrogen isotope exchange with deuterium oxide as an inexpensive deuterium source.

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