Chemically modified and inactivated bacteria enable intra-biofilm drug delivery and long-term immunity against implant infections.

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DOI:10.1038/s41551-025-01600-8
作者：Chuang Yang,Qimanguli Saiding,Wei Chen,Soohwan An,Senfeng Zhao,Muhammad Muzamil Khan,Na Kong,Min Ge,Jianlin Shi,Han Lin,Wei Tao
文献类型：期刊论文
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Nature

Abstract：Bacterial biofilms, prevalent in human infections, present a major barrier to effective antibacterial therapy due to limited drug permeability and resistance. Here we introduce a 'trick-bact

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