Targeting lactylation reinforces NK cell cytotoxicity within the tumor microenvironment

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DOI:10.1038/s41590-025-02178-8
作者：Jing Jin,?Peidong Yan,?Dongyao Wang,?Lin Bai,?Hao Liang,?Xiaoyu Zhu,?Huaiping Zhu,?Chen Ding,?Haiming Wei,?Yi Wang
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：Dysfunction of natural killer (NK) cells can be associated with tumor-derived lactate in the tumor microenvironment. Lactate-induced lysine lactylation (Kla) is a posttranslational modificat

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