Payload Diversification Overcomes Resistance and Guides Sequential Antibody-Drug Conjugate Therapy in Breast Cancer

已完结 40 由达姆发布于 2026/2/4 9:08:03

DOI:10.1158/1078-0432.ccr-25-3321
作者：Dileep Reddy. Rampa, Minji Seo, Nanae Ogata, Zhaoxuan Yang, Nithya Sridhar, Fujii Takeo, Chalothorn Wannaphut, Jennifer A. Maynard, Kyoji Tsuchikama, George W. Sledge, Naoto T. Ueno, Jangsoon Lee
文献类型：期刊论文
补充材料：仅需补充材料

American Association for Cancer Research (AACR)

Abstract：Purpose: Antibody–drug conjugates (ADCs) have transformed the treatment of breast cancer. FDA-approved ADCs such as trastuzumab deruxtecan (T-DXd), sacituzumab govitecan (SG), and datopotama

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