Dapagliflozin attenuates diabetic cardiomyopathy via NRF2 protein upregulation-driven glutathione synthesis to inhibit myocardial ferroptosis

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DOI:10.1016/j.lfs.2025.123819
作者：Xuepin Chen ,?Tianying Wang ,?Yan Gao ,?Guoan Wang ,?Likun Zhuang ,?Xi Liu ,?Li Gong ,?Mengran Wang ,?Hongyan Dai ,?Jun Guan
文献类型：期刊论文
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Elsevier

Abstract：AimsFerroptosis has emerged as a critical pathological mechanism contributing to the development and progression of type 2 diabetic cardiomyopathy (DCM). Dapagliflozin (DAPA), a sodium-gluco

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