Dapagliflozin activates the RAP1B/NRF2/GPX4 signaling and promotes mitochondrial biogenesis to alleviate vascular endothelial ferroptosis

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DOI:10.1016/j.cellsig.2025.111824
作者：Yi Zhu ,?Jin Yang ,?Jia-li Zhang ,?Hao Liu ,?Xue-jiao Yan ,?Ji-yong Ge ,?Fang-fang Wang
文献类型：期刊论文
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Elsevier

Abstract：Vascular endothelial ferroptosis is a key mechanism underlying endothelial injury and atherosclerotic plaque formation. Dapagliflozin, an essential medication in the management of heart fail

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