Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio.

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DOI:10.1002/cpt.70218
作者：Aiden-Hung P Nguyen,?Deena L Hadi,?Daniel A Todd,?Preston K Manwill,?John R White,?Matthew E Layton,?Nadja B Cech,?Kenneth E Thummel,?Mary F Paine
文献类型：期刊论文
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Abstract：Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A m

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