Synthesis and evaluation of peptide–fentanyl analogue conjugates as dual μ/δ-opioid receptor agonists for the treatment of pain

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DOI:10.1016/j.cclet.2021.11.036
作者：Jing Li ,?Tao Zhang ,?Jialin Sun ,?Fengxia Ren ,?Hongxin Jia ,?Zixing Yu ,?Jingchao Cheng ,?Weiguo Shi
文献类型：期刊论文
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Elsevier

Abstract：Novel peptide-fentanyl analogue conjugates were synthesized by the covalent coupling of carfentanyl derivatives to the C-terminus or N-terminus of the conformationally constrained dermorphin

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