Generating functionally stable and antigen-specific Treg cells from effector T cells for cell therapy of inflammatory diseases

已完结 10 由 sailor 发布于 2025/10/29 9:16:21

DOI:10.1126/scitranslmed.adr6049
作者：Norihisa Mikami,&nbsp;Ryoji Kawakami,&nbsp;Atsushi Sugimoto,&nbsp;Masaya Arai,&nbsp;Shimon Sakaguchi
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：One strategy for antigen-specific immunosuppression is to convert antigen-specific conventional T (Tconv) cells into Foxp3+ regulatory T (Treg) cells that are as stably suppressive as natura

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