IND-Enabling Studies for a TCR-T targeting a pancreatic cancer G12V KRAS mutation

已完结 20 由 bobobo 发布于 2025/10/31 15:24:46

DOI:10.1158/1078-0432.ccr-24-3086
作者：Sizhen Wang, Guangjie Yu, Yanzhenzi Dai, Chi Gan, Shuyi Qiu, Xiaohui Zhang, Xiaochun Jiang, Ran Wei, Jiongming Yang, Dou Wu, Ling Chen, Lei Huang, Min Li, Yi Xiao, Rongxi Shen, Yimin Chen, Daojun Zhu,
文献类型：期刊论文
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American Association for Cancer Research (AACR)

Abstract：Purpose: To develop adoptive T-cell therapy with genetically engineered TCR (TCR-T) that recognizes the KRAS G12V mutation, we performed an IND-enabling preclinical study of a new TCR (051).

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