Platelets mediate neutrophil infiltration and exacerbate liver injury and sinusoidal endothelial cell damage after a severe acetaminophen overdose in mice

已完结 10 由 qingjiu 发布于 2025/11/5 12:18:48

DOI:10.1007/s00204-025-04144-7
作者：Olamide B. Adelusi, Caitlin Schneider, Caylie McKimens, James P. Luyendyk, Anup Ramachandran, Hartmut Jaeschke
文献类型：期刊论文
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Springer

Abstract：Acetaminophen (APAP) overdose, the leading cause of acute liver failure in the US, is accompanied by hepatocyte necrosis and liver sinusoidal endothelial cell (LSEC) damage, with hepatic neu

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