A TH17-intrinsic IL-1β–STAT5 axis drives steroid resistance in autoimmune neuroinflammation

已完结 10 由王啊发布于 2025/11/9 9:57:36

DOI:10.1126/sciimmunol.abq1558
作者：William A. Miller-Little,?Xing Chen,?Vanessa Salazar,?Caini Liu,?Katarzyna Bulek,?Julie Y. Zhou,?Xiao Li,?Olaf Stüve,?Thaddeus Stappenbeck,?George Dubyak,?Junjie Zhao,?Xiaoxia Li
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Steroid resistance poses a major challenge for the management of autoimmune neuroinflammation. T helper 17 (TH17) cells are widely implicated in the pathology of steroid resistance; however,

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