Oxygen-Generating Transdermal Nanoplatform Codelivering BRD4 Proteolysis-Targeting Chimera/Verteporfin/CaO2 Synergistically Remodels Immunosuppressive Melanoma Microenvironment to Potentiate Combination Immunotherapy

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DOI:10.1021/acsnano.5c04580
作者：Mingli Wei, Tian Yin, Chenxiao Chu, Muse Ji, Jiansong Zhao, Xinxin Liang, Xiaoshuang Bi, Jingxin Gou, Haibing He, Xing Tang and Yu Zhang*, 
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acsnano.5c04580

American Chemical Society (ACS)

Abstract：Melanoma relapse and metastasis remain formidable clinical challenges, with the inadequate immunogenicity and highly immunosuppressive tumor microenvironment (ITME) presenting serious obstac

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