An orthogonal T7 replisome for continuous hypermutation and accelerated evolution in E. coli

已完结 10 由龙的心发布于 2025/10/11 9:25:03

DOI:10.1126/science.adp9583
作者：Christian S. Diercks, Philipp Sondermann, Cynthia Rong, Thomas G. Gillis, Yahui Ban, Celine Wang, David A. Dik, Peter G. Schultz
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Systems that perform continuous hypermutation of designated genes without compromising the integrity of the host genome can substantially accelerate the evolution of new or enhanced protein

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