CTLA-4 blockade shifts the B cell repertoire towards autoimmunity.

已完结 20 由 000 发布于 2025/10/10 15:55:07

DOI:10.1172/jci189074
作者：Elif ?akan,Meng Wang,Yile Dai,Adrien Mirouse,Clarence Rachel Villanueva-Pachas,Delphine Bouis,Joshua M Boeckers,Ruchi Gera,Sally Yraita,Leslie Clapp,Ana Luisa Perdigoto,Fabien R Delmotte,Christopher M
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1172/jci189074

Journal of Clinical Investigation (JCI)

Abstract：Checkpoint inhibitors targeting CTLA-4 and PD-1 revolutionized the treatment of cancer patients, but their use is limited by the emergence of immune-related adverse events (irAE). We assesse

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