Lentiviral Gene Therapy for Severe Leukocyte Adhesion Deficiency Type 1.

已完结 10 由 Carly Carly 发布于 2025/10/13 17:09:51

DOI:10.1056/NEJMoa2407376
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1056/nejmoa2407376

New England Journal of Medicine (NEJM)

Abstract：BACKGROUND The β2 common integrin subunit CD18 is essential for leukocyte-endothelial adhesion and extravasation to inflamed or infected tissue. Damaging variants in ITGB2, which encodes CD

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