Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis

已完结 10 由奥黛发布于 2025/10/17 14:53:25

DOI:10.1016/j.cmet.2025.09.015
作者：Artem Khan, Frederick S. Yen, Gokhan Unlu, Nicole L. DelGaudio, Ranya Erdal, Michael Xiao, Khando Wangdu, Kevin Cho, Eric R. Gamazon, Gary J. Patti, K?van? Birsoy
文献类型：期刊论文
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Elsevier

Abstract：Solute carriers (SLCs) regulate cellular and organismal metabolism by transporting small molecules and ions across membranes, yet the physiological substrates of ∼20% remain elusive. To addr

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