PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function

已完结 10 由 discoco 发布于 2025/10/19 17:31:20

DOI: 10.1038/s41589-020-0553-6
作者：Sreekanth Rajan , Yongwoo Jang , Chun-Hyung Kim , Woori Kim , Hui Ting Toh , Jeha Jeon , Bin Song , Aida Serra , Julien Lescar , Jun Yeob Yoo , Serap Beldar , Hong Ye , Congbao Kang , Xue
文献类型：期刊论文
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文献链接：https://doi.org/10.1038/s41589-020-0553-6

Nature

Abstract：The orphan nuclear receptor Nurr1 is critical for the development, maintenance and protection of midbrain dopaminergic (mDA) neurons. Here we show that prostaglandin E1 (PGE1) and its dehydr

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