Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures

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DOI:10.1016/j.cell.2025.06.047
作者：Yingjie Ding, Yuesheng Zuo, Bin Zhang, Yanling Fan, Gang Xu, Zhongyi Cheng, Shuai Ma, Shuaiqi Fang, Ao Tian, Dandan Gao, Xi Xu, Qiaoran Wang, Yaobin Jing, Mengmeng Jiang, Muzhao Xiong, Jiaming Li, Zic
文献类型：期刊论文
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Elsevier

Abstract：Proteins are the cornerstone of life. However, the proteomic blueprint of aging across human tissues remains uncharted. Here, we present a comprehensive proteomic and histological analysis o

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