Inhibition of LARP4-mediated quiescence exit of naive CD4+ T cells ameliorates autoimmune and allergic diseases.

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DOI:10.1038/s41551-025-01514-5
作者：Jian Zhou,Di Yang,Chao Han,Hui Dong,Shufeng Wang,Xiang Li,Jun Hu,Cui Wang,Jie Luo,Zhiyuan Wei,Taiping Liu,Shuai Xu,Chen Xu,Yiwei Zhang,Xian Wang,Yuanyu Deng,Baiqing Li,Ruihan Mao,Mingyang Zhang,Yi Sun
文献类型：期刊论文
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Nature

Abstract：Naive T cells are maintained under a quiescent state, and their exit from quiescence is a hallmark of antigen stimulation. Here we identify the RNA binding protein La-related protein 4 (LARP

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