Multi-target potential of newly designed tacrine-derived cholinesterase inhibitors: Synthesis, computational and pharmacological study

已完结 10 由乐发布于 2025/10/21 16:46:14

DOI:10.1016/j.bmc.2024.117649
作者：Ivana I. Jevti? ,?Relja V. Suru?i? ,?Gordana Tovilovi?-Kova?evi? ,?Nevena Zogovi? ,?Sla?ana V. Kosti?-Raja?i? ,?Deana B. Andri? ,?Jelena Z. Penji?evi?
文献类型：期刊论文
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Elsevier

Abstract：Simple and scalable synthetic approach was used for the preparation of thirteen novel tacrine derivatives consisting of tacrine and N-aryl-piperidine-4-carboxamide moiety connected by a five

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