Cryo-EM structure of the human subcortical maternal complex and the associated discovery of infertility-associated variants

已完结 10 由 212 发布于 2026/7/24 16:22:47

DOI:10.1038/s41594-024-01396-2
作者：Pengliang Chi, Guojin Ou, Sibei Liu, Qianhong Ma, Yuechao Lu, Jinhong Li, Jialu Li, Qianqian Qi, Zhuo Han, Zihan Zhang, Qingting Liu, Li Guo,&nbs
文献类型：期刊论文
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Nature

Abstract：The functionally conserved subcortical maternal complex (SCMC) is essential for early embryonic development in mammals. Reproductive disorders caused by pathogenic variants in NLRP5, TLE6 an

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