A novel FAP-targeting antibody-exatecan conjugate improves immune checkpoint blockade by reversing immunosuppressive microenvironment in pancreatic cancer

已完结 10 由边伯贤发布于 2025/11/12 8:27:13

DOI:10.1038/s41388-025-03567-x
作者：Xiaobao Wei, Jiangchao Wu, Wanyue Cao, Qitai Chen, Zhenduo Shao, Chengyang Hu, Yize Zhang, Weining Weng, Tao Meng, Xun Meng, Tingbo Liang, Qi Zha
文献类型：期刊论文
补充材料：只需要正文

Springer

Abstract：Pancreatic cancer is a highly aggressive malignancy with a dismal prognosis, characterized by a complex tumor microenvironment that promotes immunosuppression and limits the efficacy of immu

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