Discovery of 3-(Fluoro-imidazolyl)pyridazine Derivatives as Potent STING Agonists with Antitumor Activity

已完结 10 由 .. 发布于 2025/11/13 22:28:24

DOI:10.1021/acs.jmedchem.4c01873
作者：Hui Hou, Jingyi Zhou, Qibang Sui, Changfa Zhang, Zhaoming Su, Rongrong Cui, Bin Shan, Peijia Xu, Zhengyang Chen, Bing Jiang, Manjia Li, Keke Zhang, Yajie Wang, Ning Ma, Dan Teng, Mingyue Zheng, Sulin
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Stimulator of interferon genes (STING) represents a promising therapeutic target for cancer and infectious diseases due to its ability to activate innate immune responses. Herein, we describ

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