Discovery of a Highly Potent PROTAC Degrader of p300/CBP Proteins for the Treatment of Enzalutamide-Resistant Prostate Cancer

已完结 20 由小小发布于 2025/11/21 19:10:29

DOI:10.1021/acs.jmedchem.4c01100
作者：Mengjun Ma, Mengyao Li, Chengwei Zhang, Zixuan Yang, Xiaoyu Chen, Penghui Lu, Shuangshuang Nie, Siqi Zhang, Shumin Ma, Chong Qin
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：Prostate cancer therapies against androgen receptor (AR) eventually develop lethal resistance; thus, exploring new therapeutic approaches is urgent for prostate cancer treatment. Acetyltrans

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