Immune-remodeling mRNAs expressing IRF8 or NIK generate durable antitumor immunity in multiple cancer models.

已完结 10 由钱钱发布于 2026/5/19 10:11:28

DOI:10.1038/s41587-026-03115-2
作者：A Gupta, R Das, K Reed, T Jeon, Q T C Nguyen, A Rudra, X Ge, S Trongjit, Y S Vanrobaeys, R Langer, R Weissleder, C Garris, D G Anderson
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：Although immunotherapy has benefited a subset of persons with cancer, its broader efficacy remains limited, primarily because of an immunosuppressive tumor microenvironment characterized by

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